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梁新军

访问次数:发布日期:2020-11-04

梁新军,医学博士,湖北省肿瘤医院主任医师,硕士生导师

 

研究方向

肿瘤免疫逃逸机制;肿瘤表观遗传机制

 

代表论文

1. Fu C, Liang X, Cui W, Ober-Blöbaum JL, Vazzana J, Shrikant PA, Lee KP, Clausen BE, Mellman I, Jiang A. β-Catenin in dendritic cells exerts opposite functions in cross-priming and maintenance of CD8+ T cells through regulation of IL-10. Proc Natl Acad Sci U S A. 2015 Mar 3;112(9):2823-8. doi: 10.1073/pnas.1414167112. Epub 2015 Feb 17. PMID: 25730849; PMCID: PMC4352820.

2. Liang X, Fu C, Cui W, Ober-Blöbaum JL, Zahner SP, Shrikant PA, Clausen BE, Flavell RA, Mellman I, Jiang A. β-catenin mediates tumor-induced immunosuppression by inhibiting cross-priming of CD8⁺ T cells. J Leukoc Biol. 2014 Jan;95(1):179-90. doi: 10.1189/jlb.0613330. Epub 2013 Sep 10. PMID: 24023259.

3. Pang S, Zhou Z, Yu X, Wei S, Chen Q, Nie S, Liang X, Liu L. The predictive value of integrated inflammation scores in the survival of patients with resected hepatocellular carcinoma: A Retrospective Cohort Study. Int J Surg. 2017 Jun;42:170-177. doi: 10.1016/j.ijsu.2017.04.018. Epub 2017 Apr 13. PMID: 28414120.

 

主要科研项目

1. 国家基金委:补体C3调控巨噬细胞自噬促进肺癌转移的作用和机制,55万元,2018.7-2021.12,主持人

2. 国家基金委:肺癌DCsβ-catenin上调抑制自噬诱导CD8+T细胞耐受及其机制,78万元,2016.1-2019.12,主持人

 

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